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Coronavirus drug: Gilead's $2,340 price for remdesivir sparks outrage

In the US, federal health officials have allocated the limited supply to states, but that agreement with Gilead will end after September

Coronavirus drug: Gilead's $2,340 price for remdesivir sparks outrage

In 127 poor or middle-income countries, Gilead is allowing generic makers to supply the drug; two countries are doing that for around USD 600 per treatment course

The maker of a drug shown to shorten recovery time for severely ill COVID-19 patients says it will charge USD 2,340 for a typical treatment course for people covered by government health programmes in the United States and other developed countries. Gilead Sciences announced the price Monday for remdesivir, and said the price would be USD 3,120 for patients with private insurance. The amount that patients pay out of pocket depends on insurance, income and other factors.

We're in uncharted territory with pricing a new medicine, a novel medicine, in a pandemic, Gilead's chief executive, Dan O'Day, told The Associated Press. We believe that we had to really deviate from the normal circumstances and price the drug to ensure wide access rather than based solely on value to patients, he said.

However, the price was swiftly criticised; a consumer group called it an outrage because of the amount taxpayers invested toward the drug's development. The treatment courses that the company has donated to the US and other countries will run out in about a week, and the prices will apply to the drug after that, O'Day said.

In the US, federal health officials have allocated the limited supply to states, but that agreement with Gilead will end after September. They said Monday that the government has secured more than 500,000 additional courses that Gilead will produce starting in July to supply to hospitals through September, and stressed that that does not mean the government actually was acquiring that much, just ensuring the availability.

We should have sufficient supply ... but we have to make sure it's in the right place at the right time," O'Day said. In 127 poor or middle-income countries, Gilead is allowing generic makers to supply the drug; two countries are doing that for around USD 600 per treatment course.

Remdesivir's price has been highly anticipated since it became the first medicine to show benefit in the pandemic, which has killed more than half a million people globally in six months. The drug, given through an IV, interferes with the coronavirus's ability to copy its genetic material.

In a US government-led study, remdesivir shortened recovery time by 31 per cent 11 days on average versus 15 days for those given just usual care. It had not improved survival, according to preliminary results after two weeks of followup; results after four weeks are expected soon.

The Institute for Clinical and Economic Review, a nonprofit group that analyzes drug prices, said remdesivir would be cost-effective in a range of USD 4,580 to USD 5,080 if it saved lives. But recent news that a cheap steroid called dexamethasone improves survival means remdesivir should be priced between USD 2,520 and USD 2,800, the group said.

This is a high price for a drug that has not been shown to reduce mortality, Dr Steven Nissen of the Cleveland Clinic said in an email. Given the serious nature of the pandemic, I would prefer that the government take over production and distribute the drug for free. It was developed using significant taxpayer funding. Peter Maybarduk, a lawyer at the consumer group Public Citizen, called the price an outrage.

Remdesivir should be in the public domain because the drug received at least USD 70 million in public funding toward its development, he said. The price puts to rest any notion that drug companies will 'do the right thing' because it is a pandemic, Dr. Peter Bach, a health policy expert at Memorial Sloan Kettering Cancer Center in New York said in an email.

Also read: COVID-19 update: Gilead prices coronavirus drug at $2,340 for rich countries

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